Every year, an increasing number of people both worldwide and in the United States are diagnosed with diabetes. According to the Centers for Disease Control and Prevention (CDC), almost half the population of the U.S. either has diabetes or has pre-diabetes, a condition that predisposes an individual to the development of diabetes. Diabetes is a medical condition in which the body cannot process sugar from food intake and as a result high blood sugar levels accumulate. Almost a hundred years ago, diabetes was often a fatal disease since proper treatment methods were not available.
While type 2 diabetes is more common in adults over the age of 45, younger adults can also develop the condition. According to the CDC, normal fasting blood sugar is under 99 mg/dL and fasting diabetic blood sugar level is higher than 126 mg/dL. Pre-diabetes is characterized by a blood sugar level between 100-125 mg/dL. Being aware of whether you are at increased risk for diabetes can help you adjust your lifestyle accordingly, or seek prompt treatment if needed.
Some of the adverse health effects that diabetes can cause if left untreated include:
Nerve damage (diabetic neuropathy)
Retinal damage (diabetic retinopathy)
Kidney damage (diabetic nephropathy)
What is Jardiance?
Jardiance 25mg Tablets or commonly known as empagliflozin, is a prescription drug used to maintain blood sugar at a normal level in patients with type 2 diabetes. The medication is most often prescribed along with exercise and diet to reduce the risk of an adverse cardiovascular event from occurring. It can be used as a standalone prescription drug for the treatment of type 2 diabetes, but it is also commonly prescribed in combination with metformin, insulin or sulfonylureas. Currently, there are no generic version of the medication available and the only tablet available on the market is made by Boehringer Ingelheim through a joint venture with Eli Lilly and Company.
Jardiance works by preventing the reabsorption of glucose back into the bloodstream by the kidneys. It does this by inhibiting special transporters on the renal tubules of the kidneys, called the sodium glucose co-transporter-2 (SGL-2). By inhibiting these transporters, the excess glucose in the blood is excreted through urine instead of being released back into the blood. SGL-2 inhibitors can decrease the risk of cardiovascular death in patients with diabetes by 38 percent. Jardiance is a second line therapy for diabetes treatment.
How to take Jardiance
Jardiance must be taken exactly as prescribed for you by your doctor. The medication is available as tablets in either 10 mg or 25 mg doses. The medication should be taken daily in the morning with or without food.
If you miss a dose, take it as soon as you remember. If it almost time for the next dose, skip the missed dose and take the next dose according to schedule.
Depending on whether you are taking Jardiance with any other medications that lower blood sugar, such as metformin, or synthetic insulin, the dosage and how you take the drug will be adjusted.
When taking Jardiance, it is important to let your doctor know if you have any of the following conditions:
Liver or kidney disease
Bladder infections or other urination problems
Low blood pressure
Problems with your pancreas, including surgery
Drink alcohol often
Low salt diet.
Common side effects of Jardiance
When starting any new medication, it is important to be aware of the side effects that may occur. Some side effects may be commonly experienced and are not usually a cause for medical concern. However, in some cases more severe side effects may occur that are usually rare in occurrence. If such side effects are experienced, it is important to contact your doctor immediately or get emergency medical help.
Jardiance does not usually cause hypoglycemia on its own (low sugar), but it can occur when taken in combination with other diabetic medications like insulin or sulfonylurea. Symptoms of hypoglycemia include hunger, sweating, dizziness, nausea, fast heart rate and feeling anxious or shaky. If you experience hypoglycemia, it is important to quickly remedy it with a fast-acting source of glucose like candy or fruit juice.
Other common side effects that should be reported to your doctor if you experience them include:
Bloody or cloudy urine
Change in the color, amount, or odor of vaginal discharge
Difficult, burning, or painful urination
Frequent urge to urinate
Itching, stinging, or redness of the vaginal area
Lower back pain or side pain
Pain during sexual intercourse
Drug interactions of Jardiance
Certain drugs may interact with Jardiance. You should inform your doctor or pharmacist of any medications that you are already taking. If you take any other medications for diabetes, like insulin, or a ‘diuretic’ medication, tell your doctor. People taking diuretics are at increased risk for low blood pressure when it is combined with Jardiance. This is not an exhaustive list of drug interactions.
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